It is a drug that blocks a hormone called progesterone that is needed for pregnancy to continue. Mifepristone, when used together with another medicine called misoprostol, is used to end an early pregnancy (49 days or less since your last menstrual period began).
How does it work?
Mifegyne tablets contain the active ingredient mifepristone, which is a type of medicine known as an anti-progesterone. Mifepristone acts by blocking progesterone receptors in the uterus and this reduces the effectiveness of the natural hormone progesterone.
Progesterone plays an important role in the maintainance of pregnancy such as the successful implantation of the fertilised egg into the wall of the uterus and prevention of uterine contractions during pregnancy. By blocking progesterone receptors in the uterus, mifepristone significantly reduces progesterone levels so that pregnancy cannot be maintained. Abortion may occur solely as a result of the actions of mifepristone, but surgery may also be necessary to remove the foetus.
Treatment with Mifegyne tablets is always carried out under the supervision of a doctor.
How medical abortion work?
Taking Mifepristone and a prostaglandin is a very safe and effective method which leads to a successful abortion in 98% of cases. Taking the prostaglandin may cause menstrual disorders like cramping in the lower abdomen; a pain treatment might therefore be necessary similarly to what is recommended in case of painful menstruation (ibuprofen, Diclofenac). You will take the prostaglandin tablets at home and therefore you should have enough painkillers on hand.